ETD Embedded Mass Spectrometer to Allow Analysis of Changes in Proteins` Structures

Released on = April 25, 2007, 4:05 am

Press Release Author = Shushmul Maheshwari

Industry = Healthcare

Press Release Summary = Thermo Fisher Scientific Inc.’s ETD (Electron Transfer
Dissociation) embedded mass spectrometer is anticipated to enable scientists to
analyze changes in proteins’ structures.

Press Release Body = The recently released LTQ XL linear ion trap mass spectrometer
of Thermo Fisher Scientific Inc. is expected to allow scientists to analyze the
alterations in structures of proteins, encompassing those essential to cancer tumor
growth.

This new equipment features ETD (Electron Transfer Dissociation) technology - a vast
technique for peptide fragmentation. ETD enables accurate identification of proteins
as well as provides explicit information concerning the nature and location of
changes in structure of proteins, like phosphorylation.

“We believe ETD performed on a linear ion trap is a major turning point for
the proteomics community, enabling researchers to pinpoint, identify and fully
characterize more post-transitional modificatons such as phosphorylation and
glycosylation than ever before,” Greg Herrema, president of Scientific
Instruments for Thermo Fisher Scientific said in a statement that Laboratory
Network.com published on March 9, 2007.

The ion trap technology may also be used for studying “how distinctive cells &
their proteins interact with each other in order to pass signals”. This is a
vital process joined with drug resistance, structural changes while proteins truss
together, and genes’ or other molecules’ deactivation, for instance,
siRNA (small interfering RNA). This approach may also be used in any of the cell
system that can be labeled by SILAC (Stable Isotope Labeling With Amino Acids) in
cell culture.

RNCOS report on “Bioinformatics Market Update (2006)” notifies,
“Proteomics refers to the broad study of proteins, specifically their
functions and structures. Often viewed as “next step”, proteomics has
much more complications than genomics. Proteome could be illustrated as the entirety
of proteins that exist in an organism all through its life span, or, if considered
at smaller scale, the entirety of proteins existing in a specific cell type under a
specific type of simulation.”

This research report “Bioinformatics Market Update (2006)” provides
extensive research and objective analysis of the Bioinformatics Industry. Key facts
and issues analyzed in this report include: global outlook of Bioinformatics market,
analysis of the Bioinformatics market by various segments and application areas,
their revenue and growth prospects, key drivers, opportunities for growth, and
threats to the industry, an update on the recent developments in the Bioinformatics
industry, snapshots of the key players in the Bioinformatics industry.

About RNCOS E-Services Pvt Ltd.:

RNCOS, incorporated in the year 2002, is an industry research firm. It has a team of
industry experts who analyze data collected from credible sources. They provide
industry insights and analysis that helps corporations to take timely and accurate
business decision in today\'s globally competitive environment.

For more information visit: http://www.rncos.com/Report/IM045.htm
Current Industry News: http://www.rncos.com/blog



Web Site = http://www.rncos.com

Contact Details = RNCOS E-Services Pvt Ltd.
Shushmul Maheshwari
Head of Business Development
29, 1st Floor, Patparganj Industrial Area, Delhi 92
91-11-4214-1229
info@rncos.com

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